ea0029p1142 | Neuroendocrinology | ICEECE2012
Alhader A.
, Al-Zaid F.
, AL-Ayadhi L.
Introduction: Autism is a neurodevelopmental disorder with a pathogenesis that is not completely understood. Although a genetic origin has been recognized, a potential role for environmental factors, immune dysfunctions, and variations of hormonal levels was suggested. Ghrelin is a peptide hormone which can stimulate growth hormone (GH) release by activating GH secretagogue receptor. In addition, ghrelin exerts neuroprotective effects, inhibits apoptosis in hypothalamic neuron...